Prolotherapy is an injection based regenerative treatment that delivers proliferating solutions to injured soft tissue structures (like tendons or ligaments). A proliferant is a substance that induces cell division thus restoring cells in an injured tissue. These solutions are clinically proven to form new fibrous tissue via the inflammation healing cascade.
Inflammation is one of the body’s many self-healing mechanisms. During inflammation, there is a concentration of fluid meant to quarantine an injury or infection. This fluid contains many healing mechanisms including white blood cells, platelets, cytokines, and other growth factors. By inducing inflammation on-site, prolotherapy is tricking the body into initiating a healing cascade.
Prolotherapy techniques reinforce and repair the function of otherwise incompetent structures. Proliferating solutions used in prolotherapy injections include pro-inflammatory dextrose (sugar), Platelet-rich plasma (PRP), and autologous Stem Cells (from own bone marrow or fat tissue).
Treatment of Musculoskeletal Pain
Injured soft tissues are a major source of musculoskeletal pain. Soft tissues, like tendons and ligaments, heal incompletely due to poor circulation and constant shock absorption from everyday movement. Furthermore, these injuries are difficult to diagnose with just imaging (MRI or X-ray) and require direct palpation. Prolotherapy techniques work to re-stimulate healing by triggering the inflammation. Injecting of hypertonic dextrose, for example, not only triggers inflammation but promotes collagen synthesis.