Prolotherapy is an injection based regenerative treatment that delivers proliferating solutions to injured soft tissue structures (like tendons or ligaments). A proliferant is a substance known to induce cell division thus resulting in their increased numbers. These proliferating solutions are clinically proven to induce healing by promoting the formation of new fibrous tissue via the inflammation healing cascade.
Inflammation represents one of the body’s many self-healing mechanisms. During inflammation, there is a concentration of fluid on-site meant to quarantine an injury or infection. This fluid contains many of the body’s healing mechanisms including white blood cells, platelets, cytokines, and growth factors. By inducing inflammation at a specific site, prolotherapy is basically tricking the body into initiating a healing cascade.
Prolotherapy techniques are meant to reinforce, and repair the function of an otherwise incompetent structure. Proliferating solutions used in prolotherapy injections include pro-inflammatory dextrose (sugar), Platelet-rich plasma (PRP), Autologous Stem Cells (from bone marrow or fat tissue) and many others.
Treatment of Musculoskeletal Pain
A great deal of musculoskeletal pain stems from soft tissue damage and associated pathologies. Soft tissue, like tendons and ligaments, are major shock absorbers for repetitive and acute trauma. These structures tend to go unhealed as there is poor circulation in such areas, and there is constant absorption of shock from regular body movement. Furthermore, these type of injuries are difficult to diagnose as many times the only way to detect the injury is to feel the injury, through palpation. Prolotherapy techniques which re-stimulate the inflammation healing cascade are a perfect treatment for such soft tissue pathologies. Injection of hypertonic dextrose, for example, not only triggers inflammation but has a positive effect of protein and DNA synthesis. Healing soft tissue injuries provides relief for associated pain.