Your body already knows how to heal. PRP and stem cell therapy just remind it how.
Why more patients in Santa Cruz are choosing regenerative medicine over surgery — and getting their lives back faster.
If you have been told surgery is your only option for a joint injury, chronic pain, or degenerative condition, there is something your doctor may not have mentioned: your own blood and cells may be capable of doing the job better, faster, and with far less risk. At Santa Cruz CORE, regenerative medicine is one of the most transformative services we offer, and the research behind it keeps getting stronger.
How PRP therapy works
Platelet Rich Plasma therapy starts with a simple blood draw. Your blood is placed in a centrifuge that separates and concentrates the platelets, which are packed with growth factors your body uses naturally to repair damaged tissue. That concentrated plasma is then injected precisely into the injured area — a joint, tendon, ligament, or muscle — triggering a powerful healing response right where it is needed most.
Because PRP comes entirely from your own body, the risk of adverse reactions is extremely low. Most patients begin noticing gradual improvement in pain and function within a few weeks as the body’s repair process accelerates.
How stem cell therapy works
Stem cell therapy takes regeneration a step further. Mesenchymal stem cells, often derived from bone marrow or adipose tissue, have a remarkable ability to differentiate into multiple tissue types including cartilage, tendon, and bone. When introduced into a damaged area, they do not just mask pain — they actively participate in rebuilding the tissue itself. At CORE, our regenerative medicine team led by Dr. John Grady, D.O., uses stem cell injections and prolotherapy as part of a comprehensive, personalized treatment plan.
What the research actually shows
This is not experimental medicine — the data is compelling and growing rapidly.

A 2025 meta-analysis reviewing 56 randomized controlled trials confirmed that PRP outperforms both placebo and cortisone injections for chronic joint pain at both the 6 and 12 month marks. Traditional cortisone shots only held an advantage within the first four weeks — after that, PRP patients consistently reported better function and less pain.
Surgery carries real risks that regenerative medicine avoids entirely: general anesthesia, infection, lengthy rehabilitation, scar tissue, and the possibility of hardware complications. For many conditions, studies now show PRP patients achieve nearly identical functional outcomes to surgical patients — in less time and at a fraction of the cost.
Why CORE is the right place for regenerative medicine in Santa Cruz
What makes CORE different is not just the treatment — it is everything that surrounds it. After a regenerative medicine procedure, our patients have immediate access to physical therapy, occupational therapy, personal training, chiropractic care, acupuncture, and massage therapy all under one roof. That integrated support is what turns a good treatment outcome into a complete recovery. Our team communicates across disciplines so your healing plan works as a whole, not as a series of disconnected appointments.
If you have been managing joint pain, a sports injury, or a degenerative condition and want to explore what your body is genuinely capable of healing, we would love to talk. A consultation with Dr. Grady and our team is the first step toward finding out if regenerative medicine is right for you. Call today, 831-425-9500