Ketamine Therapy

Experience the Transformative Power of Ketamine Plus at Santa Cruz Core

Santa Cruz Core is proud to introduce Ketamine Plus Therapy, an innovative and science-backed approach to mental wellness and chronic pain relief. Utilizing the Restore Ketamine Plus Infusion, this advanced treatment goes beyond traditional ketamine therapy by incorporating a proprietary blend of essential amino acids and nutrients to enhance neuroplasticity, support cellular health, and optimize results. Whether you are seeking relief from depression, anxiety, or PTSD, our expert team is dedicated to guiding you on a personalized journey toward healing and transformation.

With a focus on whole-body wellness, Ketamine Plus Therapy at Santa Cruz Core is designed to restore balance, improve resilience, and accelerate recovery. By harnessing the latest breakthroughs in neuroscience and regenerative medicine, we provide a comprehensive, evidence-based solution for those who have struggled with conventional treatments. Discover a new path to mental clarity, emotional stability, and physical well-being—experience the difference with Ketamine Plus Therapy at Santa Cruz Core.

In-person, virtual, and phone consultations available.

Core is Best

Comprehensive, Whole-Body Approach

Santa Cruz Core goes beyond traditional ketamine therapy by integrating Ketamine Plus, a cutting-edge infusion that combines ketamine with essential amino acids and nutrients to enhance neuroplasticity and cellular healing. Unlike other clinics that focus solely on symptom relief, our approach is designed to support long-term wellness, helping you achieve lasting mental and physical balance. By combining ketamine therapy with our expertise in integrative medicine, we provide a more complete and effective treatment experience.

Personalized Care in a Supportive Environment

At Santa Cruz Core, we prioritize individualized care, tailoring each Ketamine Plus treatment plan to meet your unique needs and wellness goals. Our experienced team takes the time to understand your health history and recovery journey, ensuring a compassionate and customized approach that other clinics often overlook. With a focus on patient comfort and safety, we create a warm, welcoming environment where you can heal with confidence.

A Leader in Holistic Health and Innovation

With years of experience in functional medicine and holistic wellness, Santa Cruz Core is uniquely positioned to offer ketamine therapy as part of a broader, science-backed healing plan. Unlike clinics that specialize only in ketamine infusions, we integrate multiple modalities—such as physical therapy, chiropractic care, and nutrition—to amplify your results. Our commitment to innovation and whole-body health makes us the premier choice for those seeking deeper, more sustainable healing.

Ketamine Plus

Santa Cruz CORE is excited to offer Ketamine Plus Therapy, a revolutionary advancement in ketamine treatment that enhances the brain’s natural ability to heal. Unlike standard ketamine infusions, Ketamine Plus incorporates a proprietary blend of essential amino acids and metabolic cofactors designed to maximize ketamine’s neuroplastic effects. This unique formula not only accelerates recovery from depression, anxiety, and PTSD symptoms, but also promotes long-term cellular repair, making it a more effective and lasting solution than conventional ketamine therapies.

What sets Ketamine Plus Therapy apart is its ability to restore and optimize brain function, rather than just providing temporary symptom relief. Traditional ketamine treatments focus solely on short-term mood improvement, while Ketamine Plus works at a deeper level, enhancing neurogenesis and cellular metabolism for more profound and sustained results.

At CORE, Ketamine Plus Therapy is not a one-size-fits-all treatment—it is a custom-tailored approach designed to meet each patient’s unique needs. Our expert practitioners carefully evaluate your medical history, symptoms, and wellness goals to develop a personalized plan that optimizes your results. Unlike traditional ketamine treatments, which follow a standardized protocol, Ketamine Plus is adjusted based on individual response, ensuring the right balance of ketamine, amino acids, and metabolic cofactors for maximum healing and long-term benefits. Whatever your treatment goals may be, our personalized approach ensures you receive the most effective and comprehensive care available.

Ketamine Plus Therapy at CORE is designed to treat a wide range of mental health conditions, including:

Mental Health Conditions

Additional Benefits

Meet Our Doctors

Dr. Eugene Santillano is an expert dual-certified in Addiction and Family Medicine. He has over two decades of frontline primary care experience and ten years dedicated to guiding patients through the complexities of addiction recovery. He is committed to breaking barriers in addiction treatment by expanding access to compassionate guidance and evidence-based care through remote consultations.

Dr. Santillano specializes in personalized Medication for Addiction Treatment (MAT) and is proud to provide cutting-edge therapies, including Ketamine Treatment, to support mental health recovery. His unwavering mission is to challenge stigma, reduce implicit bias in healthcare, and empower patients and providers with the tools they need for compassionate transformation.

He has published the first of a series of books designed to reshape the conversation around addiction and mental health.  Trauma-informed care means creating a treatment environment where individuals receive the recovery care they deserve—without judgment, with compassion and hope.

Ketamine is a unique medicine in mental health in that its safety and efficacy for severe depression and Suicidal ideation have been unmatched.  It is the only medication that the National Institute of Mental Health has identified as a Rapidly Acting Anti Depressant (RAAD), and since initial off-label trials using ketamine, no other medicine has been able to replicate the safety and efficacy of ketamine.  

Dr Santillano is a Certified Ketamine PLUS provider for Mental Health Treatment through the Ketamine Research Institute and has completed additional training with Dr. Phil Wolfson, the intellectual leader in Ketamine-Assisted Psychotherapy.

Do you live in the Santa Cruz or Watsonville area?

Call 831-425-9500 or email info@santacruzcore.com and mention this page to redeem!
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Erika W.
Yvonne and all other staff are amazing. I feel like a valued customer and Yvonne gives the BEST massages. And I appreciate all your safety precautions at the moment.
Charise W.
Good advice as well as adaptive workout exercises were offered. I appreciate the flexibility and non-judgmental atmosphere created! Good work!!
Emma U.
Erin was so fun to work with and he was knowledgeable and I left feeling hopeful and confident.
Adriana I.
Facility is clean and staff is knowledgeable and friendly. Heather, the massage therapist is skilled and very good at her job.
Kyriea G.
Heather is amazing and puts so much care into her massage therapy. It's is genuinely therapeutic and such a great experience each time.
Nyna R.
Therapy was so kind and gentle and nourishing, thank you so very much.
Chris W.
Great customer service, safety precautions taken.
Elaine P.
Prompt communication, friendly staff, skilled staff.
Patricia W.
Your staff is friendly and competent. Your office is well-organized. You're doing an excellent job providing a safe, sanitized environment in response to the pandemic. And Gabby, my massage therapist is wonderful! She's caring, insightful about what my body needs, and has a steady, comforting presence. Plus she has outstanding massage skills.
Paul M.
Excellent communication between the masseuse and I created awesome results.
Bridget Z.
The receptionist was incredible and so was the service. The best massage I have had and Heather gave me wonderful tips/advice. I will definitely come back again soon.
Marianne N.
Claudia gave me an amazing massage. It really helped shift my body and I slept through the night for the first time since the fire.
Catherine C.
(The practitioner) was great! Awesome foot massage. Very lovely energy.
Steve C.
Went in with back pain but left feeling alleviated and able to move better.
Polly T.
Very happy with treatment and focused attention I receive with Yvonne.
Robert L.
The staff was very welcoming and kind. I've gotten a lot of massages in my life but this last massage was fantastic and really clean. I would definitely recommend this place to anybody
Sabrina E.
Cala is a great practitioner! Zoe and other front desk staff are professional and smart, and they represent the operation beautifully. Please give them positive feedback.
Deborah G.
I really like the people who work here!
Adriana I.
Heather is professional, competent, friendly and a very good massage therapist. The facility is clean and warm, the front desk people very helpful and friendly.
Guinevere A.
Customer service is great and all massage therapists I've been with were amazing which makes me trust that you all hire great folks!

Start on Your Wellness Journey Today!

If you still have any unanswered questions feel free to call us or email and we will be sure to get back to you as soon as possible. Excited to hear from you!

Massage Therapy